PVD News

Click on any of the articles below for the latest from the PVD community.

Inflammation and its associations with aortic stiffness, coronary artery disease and peripheral artery disease in different ethnic groups: The HELIUS Study

July 7, 2021


Background: Evidence shows important ethnic differences in vascular dysfunction rates; however, the mechanisms driving these differences remain unclear. One potential factor is the ethnic differences in the role of inflammation in vascular injury. We tested the hypothesis that low-grade inflammation is unequally associated with vascular dysfunction in different ethnic groups.

Peripheral Artery Disease and Abdominal Aortic Aneurysm: The Forgotten Diseases in COVID-19 Pandemic. Results from an Observational Study on Real-World Management

July 6, 2021


It is well established that patients with peripheral artery disease (PAD) as well abdominal aortic aneurysm (AAA) have an increased cardiovascular (CV) mortality. Despite this higher risk, PAD and AAA patients are often suboptimality treated. This study assessed the CV profile of PAD and AAA patients, quantifying the survival benefits of target-based risk-factors modification even in light of the COVID-19 pandemic.

Can HbA1c Variability Predict Diabetic Complications?

July 6, 2021


A study was conducted to assess if HbA1c variability impacts the incidence of diabetic complications, all-cause and cardiovascular mortality.

Increased variability in HbA1c has been associated with higher rates of diabetic complications and mortality. These significant fluctuations in HbA1c may increase mortality risk, especially in higher-risk populations such as geriatric patients. It is also unknown whether periods of hypoglycemia have negative impacts on organ function.

Study Reveals Ethnic Differences in Risk of Diabetes-related Lower Limb Complications

June 29, 2021


A recent study conducted on diabetic multi-ethnic Asian population revealed important ethnic differences in diabetes-related lower extremity complications (DRLECs). The study, published in the journal Diabetologia, found Malays to most likely to progress to DRLEC. Asian people have a different risk of diabetes progression and complications compared to those of European ancestry.

Risk for post-thrombotic syndrome after lower-limb deep vein thrombosis: location of the thrombus or residual thrombi?

June 28, 2021


Many works aimed to determine factors that influence the onset of postthrombotic syndrome after an acute episode of deep venous thrombosis. We aimed to compare the prognostic value of the most proximal extent of thrombus (proximal and distal DVT) versus the residual thrombosis as identified by venous ultrasonography performed during follow-up. We conducted a retrospective study of prospectively collected 1183 consecutive cohort patients in the RIETE registry after a first episode of deep venous thrombosis and assessed for postthrombotic syndrome after 12 months.

Safety and effectiveness of Phoenix atherectomy for endovascular treatment in calcified common femoral artery lesions

June 22, 2021


Background: Traditionally endarterectomy has been considered as the gold standard technique for the treatment of common femoral artery (CFA) lesions. The aim of this study is to investigate the procedural safety and mid-term outcomes of minimal invasive Phoenix atherectomy for the treatment of CFA lesions.

Older Age, Diabetes Duration, and CAD Are Leading Risk Factors for PAD in Patients With T2DM

June 7, 2021


Factors contributing significantly to the risk for peripheral arterial disease (PAD) among patients with type 2 diabetes include age ≥70 years, diabetes duration ≥5 years, history of coronary artery disease (CAD), hypertension, and increased low-density lipoprotein (LDL) level, according to research presented at the 30th Annual Scientific and Clinical Congress of the American Association of Clinical Endocrinologists (ENVISION 2021).

Most COVID-19 Cases in Solid Organ Transplant Patients Occur in KTRs

June 7, 2021


Investigators who reviewed data from the largest cohort to date of solid organ transplant (SOT) recipients with COVID-19 found that the viral illness is more likely to occur among those who receive kidney rather than other solid organs, according to a presentation at the virtual 2021 American Transplant Congress.

Philips’ Tack Endovascular System Shows Sustained Efficacy in 2-Year TOBA II BTK Data

June 3, 2021


Royal Philips announced results from the Tack Optimized Balloon Angioplasty (TOBA) II below-the-knee (BTK) clinical trial of the company’s Tack endovascular system (4F), a dissection repair device. In the trial, the Tack system demonstrated a sustained treatment effect and positive impact on quality of life at 2 years in the treatment of peripheral artery disease (PAD) and critical limb ischemia (CLI) patients.

Intravascular ultrasound-guided catheter-based aspiration thrombectomy in patients with acute submassive pulmonary embolism: A case series

May 19, 2021


Contrast pulmonary angiography by hand injection or power injection is widely used during catheter-based therapies for acute submassive and massive pulmonary embolism (PE). Particularly, in patients with pre-existing chronic kidney disease, this approach may present a prognostic challenge owing to a double-contrast load, initially during computed tomographic pulmonary angiography (CTPA), and during percutaneous treatment. Intravascular ultrasound (IVUS) has been used as an adjunctive imaging modality in the percutaneous treatment of chronic thromboembo...


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