PVD News

Click on any of the articles below for the latest from the PVD community.

New roadmap to lower the risk of amputation in peripheral artery disease

May 14, 2024


Early diagnosis and treatment of peripheral artery disease (PAD) are essential to prevent amputations and cardiovascular issues. New guidelines emphasize the need to address disparities in amputation and revascularization procedures to help improve outcomes for all PAD patients. Early diagnosis, a multispecialty approach, and targeted treatments are crucial. Special focus on at-risk groups is essential for better management and outcomes.

Quality of Life in Patients With Chronic Limb-Threatening Ischemia Treated With Revascularization

April 17, 2024


In the BEST-CLI trial (Best Endovascular Versus Best Surgical Therapy for Patients With Chronic Limb-Threatening Ischemia), a prespecified secondary objective was to assess the effects of revascularization strategy on health-related quality of life (HRQoL).

Intravascular Ultrasound Outperforms Angiography for Peripheral Artery Disease Treatment

April 8, 2024


3D imaging approach improves outcomes with procedure to open clogged arteries in the leg.

Below-the-Knee Endovascular Revascularization: A Position Statement

January 17, 2024


Patients with chronic limb-threatening ischemia, the terminal stage of peripheral artery disease, are frequently afflicted by below-the-knee disease. Although all patients should receive guideline-directed medical therapy, restoration of inline flow is oftentimes necessary to avoid limb loss. Proper patient selection and proficiency in endovascular techniques for below-the-knee revascularization are intended to prevent major amputation and promote wound healing. This review, a consensus among an international panel of experienced operators, provide...

Intravascular Ultrasound Use in Peripheral Arterial and Deep Venous Interventions: Multidisciplinary Expert Opinion From SCAI/AVF/AVLS/SIR/SVM/SVS

January 9, 2024


Percutaneous revascularization is the primary strategy for treating lower extremity venous and arterial disease. Angiography is limited by its ability to accurately size vessels, precisely determine the degree of stenosis and length of lesions, characterize lesion morphology, or correctly diagnose postintervention complications. These limitations are overcome with use of intravascular ultrasound (IVUS). IVUS has demonstrated the ability to improve outcomes following percutaneous coronary intervention, and there is increasing...

Successful Intravascular Ultrasound-Guided Thrombus Removal and Angioplasty for Phlegmasia Cerulea Dolens in a Young Male With a History of Multiple Lower Extremity Deep Vein Thrombosis

May 30, 2023


Phlegmasia cerulea dolens is a rare and severe form of deep venous thrombosis (DVT), characterized by an extensive thrombus burden and compromised venous outflow. We present the case of a 28-year-old male with a history of bilateral lower extremity DVTs and multiple venous stents who presented with acute-onset pain and swelling in the left lower extremity. Diagnostic imaging confirmed an acute DVT extending throughout the left lower extremity, including the external iliac vein. Given the diagnosis of phlegmasia cerulea dolens, a multidisciplinary approach involving interventional cardio...

A vein bypass first versus a best endovascular treatment first revascularisation strategy for patients with chronic limb threatening ischaemia who required an infra-popliteal...

April 25, 2023


Chronic limb-threatening ischaemia is the severest manifestation of peripheral arterial disease and presents with ischaemic pain at rest or tissue loss (ulceration, gangrene, or both), or both. We compared the effectiveness of a vein bypass first with a best endovascular treatment first revascularisation strategy in terms of preventing major amputation and death in patients with chronic limb threatening ischaemia who required an infra-popliteal, with or without an additional more proximal infra-inguinal, revascularisation procedure to restore limb perfusion.

Transcatheter Arterialization of Deep Veins in Chronic Limb-Threatening Ischemia

March 30, 2023


BACKGROUND Approximately 20% of patients with chronic limb-threatening ischemia have no revascularization options, leading to above-ankle amputation. Transcatheter arterialization of the deep veins is a percutaneous approach that creates an artery-to-vein connection for delivery of oxygenated blood by means of the venous system to the ischemic foot to prevent amputation.

Sleep duration, daytime napping, and risk of peripheral artery disease: multinational cohort and Mendelian randomization studies

March 16, 2023


Sleep duration has been associated with cardiovascular disease, however the effect of sleep on peripheral artery disease (PAD) specifically remains unestablished. We conducted observational and Mendelian randomization (MR) analyses to assess the associations of sleep duration and daytime napping with PAD risk.

Surgery vs. endovascular intervention for critical limb ischemia in the BEST-CLI trial

November 21, 2022


We spoke with BEST-CLI trial principal investigators Alik Farber, MD, from Boston Medical Center; Matthew Menard, MD, from Brigham and Women's Hospital; and Ken Rosenfield, MD, from Mass General Hospital during the American Heart Association’s Scientific Sessions 2022 conference in Chicago The trial looked at endovascular versus bypass surgery in patients with critical limb ischemia (CLI) to see which treatment option is better.


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